Affiliation:
1. Dipartimento di Farmacia-Scienze del Farmaco, Campus “E. Quagliariello”, University of Bari Aldo Moro, Via E. Orabona 4, 70126 Bari, Italy
Abstract
In this study, we report the synthesis of N-(2-(benzylamino)ethyl)-4-(naphthalene-1-sulfonamido)benzamide, designed on the basis of the structures of the PPARγ partial agonist SR2067 and of the commercial acetylcholinesterase inhibitor drug donepezil, aiming for a multi-target approach for the therapy of elderly diseases, such as diabetes and Alzheimer’s disease. The compound was fully characterized by using 1H and 13C NMR, FT-IR and HRMS.
Funder
University of Bari Aldo Moro, Fondo ordinario Ricerca scientifica