Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 2. Synthesis and Structure−Activity Relationship of Potent and Selective Cannabinoid-2 Receptor Agonists Endowed with Analgesic Activity in Vivo-Reference-Cited by-同舟云学术

Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 2. Synthesis and Structure−Activity Relationship of Potent and Selective Cannabinoid-2 Receptor Agonists Endowed with Analgesic Activity in Vivo

Published:2008-08-01 Issue:16 Volume:51 Page:5075-5084
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pasquini Serena¹,Botta Lorenzo¹,Semeraro Teresa¹,Mugnaini Claudia¹,Ligresti Alessia¹,Palazzo Enza¹,Maione Sabatino¹,Di Marzo Vincenzo¹,Corelli Federico¹

Affiliation:

1. Dipartimento Farmaco Chimico Tecnologico, Università degli Studi di Siena, Via A. Moro, 53100 Siena, Italy, Endocannabinoid Research Group, Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, Via dei Campi Flegrei 34, 80078 Pozzuoli (Naples), Italy, and Department of Experimental Medicine, Section of Pharmacology “L. Donatelli”, Second University of Naples, Via S. Maria di Costantinopoli 16, 80138 Naples, Italy

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800552f

Reference37 articles.

1. Cannabinoids in medicine: A review of their therapeutic potential

2. The endocannabinoid system and its therapeutic exploitation

3. The Endocannabinoid System: Drug Targets, Lead Compounds, and Potential Therapeutic Applications

4. Keynote review: Medicinal chemistry strategies to CB1 cannabinoid receptor antagonists

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