Affiliation:
1. Key Laboratory of Geriatric Nutrition and Health, Beijing Advanced Innovation Center for Food Nutrition and Human Health, National Soybean Processing Industry Technology Innovation Center, Beijing Technology and Business University, Beijing 100048, China
2. Beijing Science Sun Pharmaceutical Co., Ltd., Beijing 100176, China
Abstract
Mushroom bioactive peptides (MBPs) are bioactive peptides extracted directly or indirectly from edible mushrooms. MBPs are known to have antioxidant, anti-aging, antibacterial, anti-inflammatory and anti-hypertensive properties, and facilitate memory and cognitive improvement, antitumour and anti-diabetes activities, and cholesterol reduction. MBPs exert antioxidant and anti-inflammatory effects by regulating the MAPK, Keap1-Nrf2-ARE, NF-κB and TNF pathways. In addition, MBPs exert antibacterial, anti-tumour and anti-inflammatory effects by stimulating the proliferation of macrophages. The bioactivities of MBPs are closely related to their molecular weights, charge, amino acid compositions and amino acid sequences. Compared with animal-derived peptides, MBPs are ideal raw materials for healthy and functional products with the advantages of their abundance of resources, safety, low price, and easy-to-achieve large-scale production of valuable nutrients for health maintenance and disease prevention. In this review, the preparation, bioactivities, mechanisms and structure–activity relationships of MBPs were described. The main challenges and prospects of their application in functional products were also discussed. This review aimed to provide a comprehensive perspective of MBPs.
Funder
National Natural Science Foundation of China
Subject
Plant Science,Health Professions (miscellaneous),Health (social science),Microbiology,Food Science
Reference136 articles.
1. A Review on Bioactive Peptides: Physiological Functions, Bioavailability and Safety;Bhandari;Int. J. Pept. Res. Ther.,2019
2. Martinez-Villaluenga, C., Peñas, E., and Frias, J. (2017). Fermented Foods in Health and Disease Prevention, Elsevier.
3. Bioactive peptides derived from egg proteins: A review;Liu;Crit. Rev. Food Sci. Nutr.,2018
4. Bioactive peptides from meat muscle and by-products: Generation, functionality and application as functional ingredients;Lafarga;Meat Sci.,2014
5. Meta-Analysis for Correlating Structure of Bioactive Peptides in Foods of Animal Origin with Regard to Effect and Stability;Maestri;Compr. Rev. Food Sci. Food Saf.,2019
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