1. Department of Medicine and Molecular Science (M.U., S.O., E.Y., T.S., K.H., M.Y., H.S., M.M.), Gunma University Graduate School of Medicine, Maebashi, Gunma 371-8511, Japan
2. Gunma University Health and Medical Center (K.O.), Maebashi, Gunma 371-8510, Japan
3. Department of Pharmacological Sciences (J.E.P.), Stony Brook University, Stony Brook, New York 11794-8651