PTP‐MEG2 regulates quantal size and fusion pore opening through two distinct structural bases and substrates

Author:

Xu Yun‐Fei12ORCID,Chen Xu3ORCID,Yang Zhao1,Xiao Peng1,Liu Chun‐Hua4,Li Kang‐Shuai12,Yang Xiao‐Zhen5,Wang Yi‐Jing1,Zhu Zhong‐Liang6,Xu Zhi‐Gang7,Zhang Sheng8,Wang Chuan9,Song You‐Chen10,Zhao Wei‐Dong11ORCID,Wang Chang‐He12,Ji Zhi‐Liang5,Zhang Zhong‐Yin8,Cui Min3ORCID,Sun Jin‐Peng1ORCID,Yu Xiao3ORCID

Affiliation:

1. Key Laboratory Experimental Teratology of the Ministry of Education and Department of Biochemistry and Molecular Biology Shandong University School of Medicine Jinan China

2. Department of General Surgery Qilu Hospital of Shandong University Jinan China

3. Key Laboratory Experimental Teratology of the Ministry of Education and Department of Physiology Shandong University School of Medicine Jinan China

4. Department of Physiology Shandong First Medical University Taian China

5. State Key Laboratory of Cellular Stress Biology School of Life Sciences Xiamen University Xiamen China

6. School of Life Sciences University of Science and Technology of China Hefei China

7. Shandong Provincial Key Laboratory of Animal Cells and Developmental Biology School of Life Sciences Shandong University Jinan China

8. Departments of Medicinal Chemistry and Molecular Pharmacology and of Chemistry, Center for Cancer Research, and Institute for Drug Discovery Purdue University West Lafayette IN USA

9. Department of Pharmacology Hebei Medical University Shijiazhuang China

10. Department of Medical Biophysics University of Toronto Toronto ON Canada

11. Department of Developmental Cell Biology China Medical University Shenyang China

12. Center for Mitochondrial Biology and Medicine The Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi’an Jiaotong University Xi’an China

Funder

National Natural Science Foundation of China

Fundamental Research Fund of Shandong University

Natural Science Foundation of Shandong Province

National Science Fund for Distinguished Young Scholars

National Institutes of Health

China Postdoctoral Science Foundation

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

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