Dual DNA topoisomerase 1 and tyrosyl‐DNA phosphodiesterase 1 inhibition for improved anticancer activity-Reference-Cited by-同舟云学术

Dual DNA topoisomerase 1 and tyrosyl‐DNA phosphodiesterase 1 inhibition for improved anticancer activity

Published:2019-04-19 Issue:4 Volume:39 Page:1427-1441
ISSN:0198-6325
Container-title:Medicinal Research Reviews
language:en
Short-container-title:Med Res Rev

Author:

Zakharenko Alexandra¹,Dyrkheeva Nadezhda¹,Lavrik Olga¹²^ORCID

Affiliation:

1. Laboratory of Bioorganic Chemistry of EnzymesInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of SciencesNovosibirsk Russian Federation

2. Department of Natural SciencesNovosibirsk State UniversityNovosibirsk Russian Federation

Funder

Russian Foundation for Basic Research

Publisher

Wiley

Subject

Drug Discovery,Pharmacology,Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/med.21587

Reference85 articles.

1. The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily

2. Pathways for repair of topoisomerase I covalent complexes inSaccharomyces cerevisiae

3. Yeast Gene for a Tyr-DNA Phosphodiesterase that Repairs Topoisomerase I Complexes

4. A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases.

5. Tyrosyl-DNA phosphodiesterase I resolves both naturally and chemically induced DNA adducts and its potential as a therapeutic target

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