Chromatographic clarification overcomes chromatin‐mediated hitch‐hiking interactions on Protein A capture column-Reference-Cited by-同舟云学术

Chromatographic clarification overcomes chromatin‐mediated hitch‐hiking interactions on Protein A capture column

Published:2020-08-03 Issue:11 Volume:117 Page:3413-3421
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnology and Bioengineering

Author:

Van de Velde Joris¹^ORCID,Saller Manfred J.²,Eyer Kurt³,Voloshin Alexei⁴

Affiliation:

1. Separation and Purification Sciences Division 3M Belgium NV/SA Antwerp Belgium

2. Polpharma Biologics Utrecht The Netherlands

3. Bioprocesses, Pharmaplan AG Basel Switzerland

4. Separation and Purification Sciences Division, 3M Company 3M Center Saint Paul Minnesota

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.27513

Reference19 articles.

1. A novel approach to monitor clearance of host cell proteins associated with monoclonal antibodies

2. Anion‐exchange chromatographic clarification bringing simplification, robustness, and savings to mAb purification;Castro‐Forero A. A.;BioProcess International,2015

3. Knockout of a difficult‐to‐remove CHO host cell protein, lipoprotein lipase, for improved polysorbate stability in monoclonal antibody formulations

4. The effect of feed quality due to clarification strategy on the design and performance of protein A periodic counter‐current chromatography

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