The effect of feed quality due to clarification strategy on the design and performance of protein A periodic counter‐current chromatography

Author:

El‐Sabbahy Hani1,Ward David2,Ogonah Olotu2,Deakin Lynne1,Jellum Gregory M.3,Bracewell Daniel G.4ORCID

Affiliation:

1. Separation and Purification Sciences Div.3M United Kingdom PLC, 3M Centre Bracknell RG12 8HT U.K.

2. Dept. of Biochemical EngineeringUniversity College London London WC1E 6BT U.K.

3. Separation and Purification Sciences Div.3M Centre St. Paul MN 55144

4. Dept. of Biochemical EngineeringUniversity College London London WC1E 6BT UK

Funder

3M

Engineering and Physical Sciences Research Council

University College London

Publisher

Wiley

Subject

Biotechnology

Reference26 articles.

1. White Paper on Continuous Bioprocessing May 20–21 2014 Continuous Manufacturing Symposium

2. Design and control of integrated chromatography column sequences

3. El‐SabbahyH. The challenges of continuous multicolumn protein A chromatography.EPM Mag.2017.https://www.epmmagazine.com/api/content/e2e30736‐e023‐11e7‐9882‐121bebc5777e/. Accessed January 2 2018.

4. Continuous downstream processing of biopharmaceuticals

5. EstesKA LangerE.Update on Continuous Bioprocessing: From the Industry's Perception to Reality.http://www.pharmtech.com/update‐continuous‐bioprocessing‐industry‐s‐perception‐reality‐0. Accessed January 4 2018.

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