Validation of an LC-MS/MS method for simultaneous detection of four HDAC inhibitors - belinostat, panobinostat, rocilinostat and vorinostat in mouse plasma and its application to a mouse pharmacokinetic study

Author:

Giri Kalpesh Kumar1,Suresh P. S.1,Saim Syed Mohd1,Zainuddin Mohd1,Bhamidipati Ravi Kanth1,Dewang Purushottam2,Hallur Mahanandeesha S.2,Rajagopal Sridharan2,Rajagopal Sriram1,Mullangi Ramesh1

Affiliation:

1. Drug Metabolism and Pharmacokinetics, Jubilant Biosys Ltd, Industrial Suburb; Bangalore India

2. Department of Medicinal Chemistry; Jubilant Biosys Ltd, Industrial Suburb; Bangalore India

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference24 articles.

1. Abhay , G. Bharati , C 2009 Novel process for the preparation of vorinostat

2. The effects of sample preparation methods on the variability of the electrospray ionization response for model drug compounds;Bonfiglio;Rapid Communications in Mass Spectrometry,1999

3. High turbulence liquid chromatography online extraction and tandem mass spectrometry for the simultaneous determination of suberoylanilide hydroxamic acid and its two metabolites in human serum;Du;Rapid Communications in Mass Spectrometry,2005

4. Duzer , V. J. H. Ralph , M. Walter , O. James , E. B. Guoxiang , H. Dejian , X. Nan , Y 2011 Reverse amide compounds as protein deacetylase inhibitors and methods of use thereof

5. Development and validation of ultra high performance liquid chromatography-mass spectrometry method for LBH589 in mouse plasma and tissues;Estella-Hermoso de Mendoza;Journal of Chromatography B,2011

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3