Identification and characterization of new degradation products of belinostat using UHPLC-Q-TOF-MS/MS and in silico toxicity prediction-Reference-Cited by-同舟云学术

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Identification and characterization of new degradation products of belinostat using UHPLC-Q-TOF-MS/MS and in silico toxicity prediction

Published:2021-04-03 Issue:5-6 Volume:44 Page:285-297
ISSN:1082-6076
Container-title:Journal of Liquid Chromatography & Related Technologies
language:en
Short-container-title:Journal of Liquid Chromatography & Related Technologies

Author:

Mehta Lovekesh¹,Naved Tanveer¹,Grover Parul²,Bhardwaj Monika³⁴,Mukherjee Debaraj³,Vennapu Dushyanth R.⁵

Affiliation:

1. Amity Institute of Pharmacy, Amity University, Noida, India

2. KIET School of Pharmacy, KIET Group of Institutions, Delhi-NCR, Ghaziabad, India

3. Natural Product Chemistry Division, Indian Institute of Integrative Medicine, Jammu, India

4. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India

5. Department of Pharmaceutical Chemistry, KLE University College of Pharmacy, Belagavi, India

Publisher

Informa UK Limited

Subject

Clinical Biochemistry,Pharmaceutical Science,Biochemistry,Analytical Chemistry

Link

https://www.tandfonline.com/doi/pdf/10.1080/10826076.2021.1906271

Reference28 articles.

1. Novel Sulfonamide Derivatives as Inhibitors of Histone Deacetylase

2. Role of Histone Deacetylases and Their Inhibitors in Cancer Biology and Treatment

3. Belinostat: a new broad acting antineoplastic histone deacetylase inhibitor

4. Final Results of a Phase II Trial of Belinostat (PXD101) in Patients with Recurrent or Refractory Peripheral or Cutaneous T-Cell Lymphoma.

5. 7105 POSTER DISCUSSION Belinostat in Combination With Carboplatin and Paclitaxel (BelCaP) for Treatment of Bladder Cancer – A Pharmacokinetic Study of Exposure to Belinostat and Its Metabolites

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