First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation-Reference-Cited by-同舟云学术

First-in-Class Hydrazide-Based HDAC6 Selective Inhibitor with Potent Oral Anti-Inflammatory Activity by Attenuating NLRP3 Inflammasome Activation

Published:2022-09-08 Issue:18 Volume:65 Page:12140-12162
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yue Kairui¹,Sun Simin¹,Jia Geng¹,Qin Mengting¹,Hou Xiaohan¹,Chou C. James²^ORCID,Huang Chao¹,Li Xiaoyang¹³^ORCID

Affiliation:

1. Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266071, China

2. Department of Drug Discovery and Biomedical Sciences, College of Pharmacy, Medical University of South Carolina, Charleston, South Carolina 29425, United States

3. Laboratory for Marine Drugs and Bioproducts, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266003, China

Funder

Central University Basic Research Fund of China

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00853

Reference52 articles.

1. Physical and Functional HAT/HDAC Interplay Regulates Protein Acetylation Balance

2. Histone deacetylases (HDACs): characterization of the classical HDAC family

3. Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug

4. Belinostat: First Global Approval

5. Panobinostat: First Global Approval

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Biological and structural investigation of tetrahydro-β-carboline-based selective HDAC6 inhibitors with improved stability;European Journal of Medicinal Chemistry;2024-10

2. Novel access to α-carbolines with biological applications;European Journal of Medicinal Chemistry;2024-10

3. Biological function and small molecule inhibitors of histone deacetylase 11;European Journal of Medicinal Chemistry;2024-10

4. Small molecules targeting HDAC6 for cancer treatment: Current progress and novel strategies;Biomedicine & Pharmacotherapy;2024-09

5. Psammaplin A analogues with modified disulfide bond targeting histone deacetylases: Synthesis and biological evaluation;European Journal of Medicinal Chemistry;2024-09