Interleukin-17 promotes development of castration-resistant prostate cancer potentially through creating an immunotolerant and pro-angiogenic tumor microenvironment

Author:

Zhang Qiuyang1,Liu Sen1,Zhang Qingsong12,Xiong Zhenggang3,Wang Alun R.3,Myers Leann4,Melamed Jonathan5,Tang Wendell W.6,You Zongbing12789ORCID

Affiliation:

1. Department of Structural & Cellular Biology; Tulane University; New Orleans Louisiana

2. Department of Orthopaedic Surgery; Tulane University; New Orleans Louisiana

3. Department of Pathology and Laboratory Medicine; School of Medicine; Tulane University; New Orleans Louisiana

4. Department of Biostatistics and Bioinformatics; School of Public Health and Tropical Medicine; Tulane University; New Orleans Louisiana

5. Department of Pathology; New York University School of Medicine; New York New York

6. Department of Pathology; Ochsner Clinic Foundation; New Orleans Louisiana

7. Tulane Cancer Center and Louisiana Cancer Research Consortium; Tulane University; New Orleans Louisiana

8. Tulane Center for Stem Cell Research and Regenerative Medicine; Tulane University; New Orleans Louisiana

9. Tulane Center for Aging; Tulane University; New Orleans Louisiana

Publisher

Wiley

Subject

Urology,Oncology

Reference49 articles.

1. Androgen deprivation therapy: Progress in understanding mechanisms of resistance and optimizing androgen depletion;Harris;Nat Clin Pract Urol,2009

2. Androgen receptor gene mutations in human prostate cancer;Newmark;Proc Natl Acad Sci USA,1992

3. The androgen axis in recurrent prostate cancer;Mohler;Clin Cancer Res,2004

4. Ligand-independent androgen receptor variants derived from splicing of cryptic exons signify hormone-refractory prostate cancer;Hu;Cancer Res,2009

5. Androgen receptor activation in prostatic tumor cell lines by insulin-like growth factor-I, keratinocyte growth factor, and epidermal growth factor;Culig;Cancer Res,1994

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