Prediction of Human Pharmacokinetic Profile in Animal Scale up Based on Normalizing Time Course Profiles
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference28 articles.
1. Prediction of human clearance from animal data and molecular structural parameters using multivariate regression analysis;Wajima;J Pharm Sci,2002
2. Prediction of human pharmacokinetics from animal data and molecular structural parameters using multivariate regression analysis: volume of distribution at steady state;Wajima;J Pharm Pharmacol,2003
3. Interspecies correlation of plasma concentration, history of methotrexate (NSC-740);Dedrick;Cancer Chemother Rep,1970
4. Interspecies pharmacokinetic scaling and the evolutionary-comparative paradigm;Boxenbaum;Drug Metab Rev,1984
5. Interspecies pharmacokinetic scaling and the Dedrick plots;Boxenbaum;Am J Physiol,1983
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