Prediction of Human Clearance from Animal Data and Molecular Structural Parameters using Multivariate Regression Analysis
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference75 articles.
1. Interspecies scaling, allometry, physiological time and the grand plan of pharmacokinetics;Boxenbaum;J Pharmacokinet Biopharm,1982
2. Interspecies pharmacokinetic scaling and the evolutionary-comparative paradigm;Boxenbaum;Drug Metab Rev,1984
3. Allometric issues in drug development;Mahmood;J Pharm Sci,1999
4. Interspecies pharmacokinetic scaling, biological design and neoteny;Boxenbaum,1990
5. Interspecies scaling in pharmacokinetics;MacNamra,1991
Cited by 61 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. The Comparison of Machine Learning and Mechanistic In Vitro–In Vivo Extrapolation Models for the Prediction of Human Intrinsic Clearance;Molecular Pharmaceutics;2023-10-09
2. Discovery of a Potent and Selective Tyrosine Kinase 2 Inhibitor: TAK-279;Journal of Medicinal Chemistry;2023-07-10
3. Development of a 2D-QSAR Model for Tissue-to-Plasma Partition Coefficient Value with High Accuracy Using Machine Learning Method, Minimum Required Experimental Values, and Physicochemical Descriptors;European Journal of Drug Metabolism and Pharmacokinetics;2023-06-02
4. Application of <i>in Silico</i> Technologies for Drug Target Discovery and Pharmacokinetic Analysis;Chemical and Pharmaceutical Bulletin;2023-06-01
5. Computational Predictions of Nonclinical Pharmacokinetics at the Drug Design Stage;Journal of Chemical Information and Modeling;2023-01-03
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3