Detection of Neutralizing Anti‐Type 1 Interferon Autoantibodies-Reference-Cited by-同舟云学术

Detection of Neutralizing Anti‐Type 1 Interferon Autoantibodies

Published:2022-08 Issue:8 Volume:2 Page:
ISSN:2691-1299
Container-title:Current Protocols
language:en
Short-container-title:Current Protocols

Author:

Shaw Elana R.¹,Rosen Lindsey B.²,Ding Li²,Holland Steven M.²,Su Helen C.²

Affiliation:

1. Human Immunological Diseases Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda Maryland

2. Immunopathogenesis Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda Maryland

Funder

National Institute of Allergy and Infectious Diseases

National Institutes of Health

Publisher

Wiley

Subject

Medical Laboratory Technology,Health Informatics,General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cpz1.511

Reference32 articles.

1. Neutralizing type‐I interferon autoantibodies are associated with delayed viral clearance and intensive care unit admission in patients with COVID‐19

2. Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

3. Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine

4. Autoantibodies against type I IFNs in patients with life-threatening COVID-19

5. Anti-CD45RC antibody immunotherapy prevents and treats experimental autoimmune polyendocrinopathy–candidiasis–ectodermal dystrophy syndrome

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