Simultaneous determination of norisoboldine and its major metabolite in rat plasma by ultra-performance liquid chromatography-mass spectrometry and its application in a pharmacokinetic study

Author:

Chen Jian-Zhong,Xu Ying,Chou Gui-Xin,Wang Chang-Hong,Yang Li,Wang Zheng-Tao

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference9 articles.

1. Characterization of new metabolites from in vivo biotransformation of norisoboldine by liquid chromatography/mass spectrometry and NMR spectroscopy;Chen;Journal of Pharmaceutical and Biomedical Analysis,2010

2. Isoquinoline alkaloids from Lindera aggregate;Chou;Chinese Journal of Natural Medicines,2005

3. Food and Drug Administration, Center for Drug Evaluation and Research Guidance for Industry: Bioanalytical Method Validation 2001 http://www.fda.gov/CVM

4. Alkaloids from Lindera aggregate;Gan;Natural Product Communications,2009

5. A rapid method for the simultaneous determination of 11 saponins in Panax notoginseng using ultra-performance liquid chromatography;Guan;Journal of Pharmaceutical and Biomedical Analysis,2007

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