Population <scp>PBPK</scp> modeling using parametric and nonparametric methods of the Simcyp Simulator, and Bayesian samplers-Reference-Cited by-同舟云学术

Population PBPK modeling using parametric and nonparametric methods of the Simcyp Simulator, and Bayesian samplers

Published:2022-04-22 Issue:6 Volume:11 Page:755-765
ISSN:2163-8306
Container-title:CPT: Pharmacometrics & Systems Pharmacology
language:en
Short-container-title:CPT Pharmacom & Syst Pharma

Author:

Wedagedera Janak R.¹,Afuape Anthonia¹,Chirumamilla Siri Kalyan¹^ORCID,Momiji Hiroshi¹^ORCID,Leary Robert¹,Dunlavey Mike¹,Matthews Richard¹,Abduljalil Khaled¹,Jamei Masoud¹^ORCID,Bois Frederic Y.¹^ORCID

Affiliation:

1. CERTARA UK Limited Simcyp Division Sheffield UK

Publisher

Wiley

Subject

Pharmacology (medical),Modeling and Simulation

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/psp4.12787

Reference45 articles.

1. A Mechanistic Framework for In Vitro–In Vivo Extrapolation of Liver Membrane Transporters: Prediction of Drug–Drug Interaction Between Rosuvastatin and Cyclosporine

2. Physiologically Based Pharmacokinetics Joined With In Vitro–In Vivo Extrapolation of ADME: A Marriage Under the Arch of Systems Pharmacology

3. A Theoretical Physiologically‐Based Pharmacokinetic Approach to Ascertain Covariates Explaining the Large Interpatient Variability in Tacrolimus Disposition

4. Can Population Modelling Principles be Used to Identify Key PBPK Parameters for Paediatric Clearance Predictions? An Innovative Application of Optimal Design Theory

5. Population pharmacokinetic reanalysis of a Diazepam PBPK model: a comparison of Stan and GNU MCSim

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