Author:
Wiese Michael,Schmalz Dietmar,Seydel Joachim K.
Subject
Drug Discovery,Pharmaceutical Science
Reference24 articles.
1. TRIMETHOPRIM, A SULPHONAMIDE POTENTIATOR
2. Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.
3. Receptor-based design of dihydrofolate reductase inhibitors: comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analogs
4. , , , , , , , , , in Chemistry and Biology of Pteridines (Ed.: ); Walter de Gruyter & Co., Berlin, 1983, pp. 505–509.
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