Folate-Synthesizing Enzyme System as Target for Development of Inhibitors and Inhibitor Combinations against Candida albicansSynthesis and Biological Activity of New 2,4-Diaminopyrimidines and 4‘-Substituted 4-Aminodiphenyl Sulfones

Author:

Otzen Thomas1,Wempe Ellen G.1,Kunz Brigitte1,Bartels Rainer1,Lehwark-Yvetot Gudrun1,Hänsel Wolfram1,Schaper Klaus-Jürgen1,Seydel Joachim K.1

Affiliation:

1. Division of Structural Biochemistry, Research Center Borstel, Leibniz Center for Medicine and Biosciences, Parkallee 1-40, D-23845 Borstel, Germany, and Pharmaceutical Institute, University of Kiel, D-24118 Kiel, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference56 articles.

1. Clinton Rules Out Some Studies

2. Invasive Candida Infections

3. Fungemia in a Cancer Hospital: Changing Frequency, Earlier Onset, and Results of Therapy

4. Mutschler, E.Arzneimittelwirkungen; Wissenschaftliche Verlagsgesellschaft:  Stuttgart, Germany, 1991.

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