The Proteome‐Wide Potential for Reversible Covalency at Cysteine-Reference-Cited by-同舟云学术

The Proteome‐Wide Potential for Reversible Covalency at Cysteine

Published:2019-08-12 Issue:33 Volume:58 Page:11385-11389
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Senkane Kristine¹,Vinogradova Ekaterina V.¹,Suciu Radu M.¹,Crowley Vincent M.¹,Zaro Balyn W.¹,Bradshaw J. Michael²,Brameld Ken A.²,Cravatt Benjamin F.¹^ORCID

Affiliation:

1. Department of ChemistryThe Scripps Research Institute La Jolla CA 92037 USA

2. Principia Biopharma 220 E. Grand Avenue South San Francisco CA 94080 USA

Funder

National Cancer Institute

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201905829

Reference38 articles.

1. The resurgence of covalent drugs

2. Developing Irreversible Inhibitors of the Protein Kinase Cysteinome

3. Covalent inhibitors in drug discovery: from accidental discoveries to avoided liabilities and designed therapies

4. Strategies for discovering and derisking covalent, irreversible enzyme inhibitors

5. Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia

Cited by 41 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Advanced technologies for screening and identifying covalent inhibitors;TrAC Trends in Analytical Chemistry;2024-09

2. Exploring 2-Sulfonylpyrimidine Warheads as Acrylamide Surrogates for Targeted Covalent Inhibition: A BTK Story;Journal of Medicinal Chemistry;2024-08-09

3. Development and Application of Reversible and Irreversible Covalent Probes for Human and Mouse Cathepsin‐K Activity Detection, Revealing Nuclear Activity;Advanced Science;2024-07-05

4. Evaluation of a Covalent Library of Diverse Warheads (CovLib) Binding to JNK3, USP7, or p53;Drug Design, Development and Therapy;2024-07

5. N‐Cyanopiperazines as Specific Covalent Inhibitors of the Deubiquitinating Enzyme UCHL1;Angewandte Chemie;2024-02-09