The Organocatalytic Approach to Enantiopure 2H- and 3H-Pyrroles: Inhibitors of the Hedgehog Signaling Pathway-Reference-Cited by-同舟云学术

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The Organocatalytic Approach to Enantiopure 2H- and 3H-Pyrroles: Inhibitors of the Hedgehog Signaling Pathway

Published:2016-05-30 Issue:27 Volume:55 Page:7693-7697
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew. Chem. Int. Ed.

Author:

Kötzner Lisa¹,Leutzsch Markus¹,Sievers Sonja²,Patil Sumersing³,Waldmann Herbert³,Zheng Yiying¹,Thiel Walter¹,List Benjamin¹

Affiliation:

1. Max-Planck-Institut für Kohlenforschung; Kaiser Wilhelm-Platz 1 45470 Mülheim an der Ruhr Germany

2. Max-Planck-Institut für Molekulare Physiologie; Compound Management and Screening Center (COMAS); Otto-Hahn-Strasse 11 44227 Dortmund Germany

3. Max-Planck-Institut für Molekulare Physiologie; Otto-Hahn-Strasse 11 44227 Dortmund Germany

Funder

Max Planck Society

Publisher

Wiley

Subject

General Chemistry,Catalysis

Reference90 articles.

1. Structure-Based Design of β-Site APP Cleaving Enzyme 1 (BACE1) Inhibitors for the Treatment of Alzheimer’s Disease

2. Design and Synthesis of β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors with in Vivo Brain Reduction of β-Amyloid Peptides

3. Biotransformation of Two β-Secretase Inhibitors Including Ring Opening and Contraction of a Pyrimidine Ring

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4. Assessing biologic/toxicologic effects of extractables from plastic contact materials for advanced therapy manufacturing using cell painting assay and cytotoxicity screening;Scientific Reports;2024-03-11

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