Protein‐Templated Formation of an Inhibitor of the Blood Coagulation Factor Xa through a Background‐Free Amidation Reaction
Author:
Affiliation:
1. Institute of Pharmacy Medicinal Chemistry Freie Universität Berlin Königin-Luise-Strasse 2+4 14195 Berlin Germany
2. Philipps-Universität Marburg Fachbereich Pharmazie Institut für Pharmazeutische Chemie Marbacher Weg 6 35037 Marburg Germany
Funder
Deutsche Forschungsgemeinschaft
Publisher
Wiley
Subject
General Chemistry,Catalysis
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201611547
Reference59 articles.
1.
2. The rise of fragment-based drug discovery
3. Fragment-Based Approaches in Drug Discovery and Chemical Biology
4. Twenty years on: the impact of fragments on drug discovery
5. Learning from our mistakes: The ‘unknown knowns’ in fragment screening
Cited by 27 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Protein‐Templated Ugi Reactions versus In‐Situ Ligation Screening: Two Roads to the Identification of SARS‐CoV‐2 Main Protease Inhibitors;Chemistry – A European Journal;2024-01-31
2. Shotgun Kinetic Target-Guided Synthesis Approach Enables the Discovery of Small-Molecule Inhibitors against Pathogenic Free-Living Amoeba Glucokinases;ACS Infectious Diseases;2023-10-11
3. Biocompatible reactions: advances in kinetic target-guided synthesis;Trends in Chemistry;2023-09
4. Linkers in fragment-based drug design: an overview of the literature;Expert Opinion on Drug Discovery;2023-07-19
5. Going beyond Binary: Rapid Identification of Protein–Protein Interaction Modulators Using a Multifragment Kinetic Target-Guided Synthesis Approach;Journal of Medicinal Chemistry;2023-03-31
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3