A Rapid Method for pKa Determination of Drugs Using Pressure-Assisted Capillary Electrophoresis with Photodiode Array Detection in Drug Discovery-Reference-Cited by-同舟云学术

A Rapid Method for pKa Determination of Drugs Using Pressure-Assisted Capillary Electrophoresis with Photodiode Array Detection in Drug Discovery

Published:2002-04 Issue:4 Volume:91 Page:933-942
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Ishihama Yasushi,Nakamura Masahiro,Miwa Toshinobu,Kajima Takashi,Asakawa Naoki

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference39 articles.

1. ElogPoct: A tool for lipophilicity determination in drug discovery;Lombardo;J Med Chem,2000

2. IAM chromatography: An in vitro screening for predicting drug membrane permeability;Pidgeon;J Med Chem,1995

3. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings;Lipinski;Adv Drug Del Rev,1996

4. A high-throughput screening method for the determination of aqueous drug solubility using laser nephelometry in microtiter plates;Bevan;Anal Chem,2000

5. pH-metric solubility: Correlation between the acid-base titration and the saturation shake-flask solubility-pH methods;Avdeef;Pharm Res,2000

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