High-throughput and reliable assessments of the ionization constant of monoprotic organic acids through an arginine based mixed mode HPLC-Reference-Cited by-同舟云学术

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High-throughput and reliable assessments of the ionization constant of monoprotic organic acids through an arginine based mixed mode HPLC

Published:2023-10 Issue: Volume:235 Page:115604
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

Russo Giacomo^ORCID,Kajtazi Ardiana,Vallaro Maura,Surmont Pieter,Ermondi Giuseppe,Anderson Scott,Grumetto Lucia,Caron Giulia,Lynen Frédéric

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference25 articles.

1. A. Avdeef, Applications and theory guide to pH-metric pKa and logP measurement, Sirius Analytical Instruments Lts.: Forest Row UK (1993).

2. Drug ionization and physicochemical profiling;Avdeef;Mol. Drug Prop.: Meas. Predict.,2007

3. Physicochemical profiling (solubility, permeability and charge state);Avdeef;Curr. Top. Med Chem.,2001

4. Introduction;Albert,1984

5. pKa determination;Avdeef,2012

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