Synthese von Bicyclo[1.1.1]pentan‐Bioisosteren von internen Alkinen und para ‐disubstituierten Benzolen unter Verwendung von [1.1.1]Propellan
Author:
Affiliation:
1. Ludwig-Maximilians-Universität München Department Chemie Butenandtstraße 5-13, Haus F 81377 München Deutschland
2. Global Discovery Chemistry Novartis Institutes for BioMedical Research Klybeckstrasse 141 4057 Basel Schweiz
Publisher
Wiley
Subject
General Medicine
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ange.201706799
Reference33 articles.
1. Bioisosteres in Medicinal Chemistry
2.
3. Synthesis and biological evaluation of 2-(3′-(1 H -tetrazol-5-yl)bicyclo[1.1.1]pent-1-yl)glycine ( S -TBPG), a novel mGlu1 receptor antagonist
4. Application of the Bicyclo[1.1.1]pentane Motif as a Nonclassical Phenyl Ring Bioisostere in the Design of a Potent and Orally Active γ-Secretase Inhibitor
5. Investigation of a Bicyclo[1.1.1]pentane as a Phenyl Replacement within an LpPLA2 Inhibitor
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