A validated LC-MS/MS method for rapid determination of brazilin in rat plasma and its application to a pharmacokinetic study

Author:

Deng Zhipeng1,Wang Xin1,Zhao Huanxin1,Cui Shuxiang1,Yao Qingqiang1,Bai Hong1

Affiliation:

1. Institute of Materia Medica; Shandong Academy of Medical Sciences; No. 18877 Jingshi Road; Jinan; 250062; People's Republic of China

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference16 articles.

1. Antioxidant activity of Caesalpinia sappan heartwood;Badami;Biological and Pharmaceutical Bulletin,2003

2. Quality standard of Sappan Lignum;Chen;China Journal of Chinese Materia Medica,2010

3. Brazilin modulates immune function mainly by augmenting T cell activity in halothane administered mice;Choi;Planta Medica,1997

4. Antioxidant activity in vitro of three constituents from Caesalpinia sappan L;Hu;Tsinghua Science and Technology,2008

5. Effects of brazilin on erythrocyte deformability and its related biochemical factors in streptozotocin induced diabetic rats;Moon;Archives of Pharmacal Research,1988

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