Time-Trajectories in Efficiency Maps as Effective Guides for Drug Discovery Efforts
Author:
Publisher
Wiley
Subject
Organic Chemistry,Computer Science Applications,Drug Discovery,Molecular Medicine,Structural Biology
Reference14 articles.
1. An Analysis of the Binding Efficiencies of Drugs and Their Leads in Successful Drug Discovery Programs
2. Ligand efficiency indices for an effective mapping of chemico-biological space: the concept of an atlas-like representation
3. Discovery and structure–activity relationships of pentanedioic acid diamides as potent inhibitors of 11β-hydroxysteroid dehydrogenase type I
4. Discovery and structure-guided drug design of inhibitors of 11β-hydroxysteroid-dehydrogenase type I based on a spiro-carboxamide scaffold
5. Bioorg. Med. Chem. Lett.
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