Proteolysis and therapeutic potential of bioactive peptides derived from Cheddar cheese

Author:

Shafique Bakhtawar1,Murtaza Mian Anjum1,Hafiz Iram2,Ameer Kashif1,Basharat Shahnai3,Mohamed Ahmed Isam A.45ORCID

Affiliation:

1. Institute of Food Science and Nutrition University of Sargodha Sargodha Pakistan

2. Institute of Chemistry University of Sargodha Sargodha Pakistan

3. The University Institute of Diet and Nutritional Sciences The University of Lahore Lahore Pakistan

4. Department of Food Science and Nutrition, College of Food and Agricultural Sciences King Saud University Riyadh Saudi Arabia

5. Department of Food Science and Technology, Faculty of Agriculture University of Khartoum Shambat Sudan

Abstract

AbstractCheddar cheese‐derived bioactive peptides are considered a potential component of functional foods. A positive impact of bioactive peptides on diet‐related chronic, non‐communicable diseases, like obesity, cardiovascular diseases, and diabetes, has been observed. Bioactive peptides possess multifunctional therapeutic potentials, including antimicrobial, immunomodulatory, antioxidant, enzyme inhibitory effects, anti‐thrombotic, and phyto‐pathological activities against various toxic compounds. Peptides can regulate human immune, gastrointestinal, hormonal, and neurological responses, which play an integral role in the deterrence and treatment of certain diseases like cancer, osteoporosis, hypertension, and other health disorders, as described in the present review. This review summarizes the categories of the Cheddar cheese‐derived bioactive peptides, their general characteristics, physiological functions, and possible applications in healthcare.

Publisher

Wiley

Subject

Food Science

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