Synthesis and characterization of 11 C-labeled benzyl amidine derivatives as PET radioligands for GluN2B subunit of the NMDA receptors-Reference-Cited by-同舟云学术

Synthesis and characterization of 11 C-labeled benzyl amidine derivatives as PET radioligands for GluN2B subunit of the NMDA receptors

Published:2018-11-18 Issue:14 Volume:61 Page:1095-1105
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J Label Compd Radiopharm

Author:

Fuchigami Takeshi¹^ORCID,Fujimoto Noriko²,Haradahira Terushi³,Nojiri Yumiko²,Okauchi Takashi⁴,Maeda Jun⁵,Suhara Tetsuya⁵,Yamamoto Fumihiko⁶,Nakayama Morio¹,Maeda Minoru⁷,Mukai Takahiro⁸

Affiliation:

1. Department of Hygienic Chemistry, Graduate School of Biomedical Sciences; Nagasaki University; Nagasaki Japan

2. Graduate School of Pharmaceutical Sciences; Kyushu University; Fukuoka Japan

3. Faculty of Pharmaceutical Sciences; Nagasaki International University; Nagasaki Japan

4. Laboratory for Biofunction Dynamics Imaging; RIKEN Center for Biosystems Dynamics Research; Kobe Japan

5. Department of Functional Brain Imaging Research; National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Science and Technology; Chiba Japan

6. Faculty of Pharmaceutical Sciences; Tohoku Medical and Pharmaceutical University; Sendai Japan

7. Daiichi University of Pharmacy; Fukuoka Japan

8. Department of Biophysical Chemistry; Kobe Pharmaceutical University; Kobe Japan

Funder

Japan Society for the Promotion of Science

the Grant-in-Aid for Young Scientists (Start-up)

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jlcr.3691/fullpdf

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5. The N-methyl-d-aspartate receptor subunit NR2B: localization, functional properties, regulation, and clinical implications;Loftis;Pharmacol Ther,2003

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