1. School of Pharmacy; Shanghai University of Traditional Chinese Medicine; 1200 Cailun Road Shanghai 201203 China
2. Key Laboratory of Receptor Research & Drug Discovery and Design Center; Shanghai Institute of Materia Medica, Chinese Academy of Sciences; 555 Zuchongzhi Road Shanghai 201203 China
3. Informatics Department; UCB Pharma; 216 Bath Road Slough SL1 4EN UK