1. Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada
2. Department of Medicine, University of Toronto, Toronto, Ontario, Canada
3. Department of Physiology, University of Toronto, Toronto, Ontario, Canada
4. Department of Cardiovascular, Metabolic and Endocrine Diseases, Pfizer Global Research and Development, Cambridge, Massachusetts
5. Banting and Best Diabetes Centre, University of Toronto, Toronto, Ontario, Canada