Design, Synthesis, and Biological Evaluation of DeuteratedC-Aryl Glycoside as a Potent and Long-Acting Renal Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes-Reference-Cited by-同舟云学术

Design, Synthesis, and Biological Evaluation of DeuteratedC-Aryl Glycoside as a Potent and Long-Acting Renal Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes

Published:2014-02-12 Issue:4 Volume:57 Page:1236-1251
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Xu Ge¹²,Lv Binhua²,Roberge Jacques Y.²,Xu Baihua²,Du Jiyan²,Dong Jiajia²,Chen Yuanwei²,Peng Kun²,Zhang Lili²,Tang Xinxing²,Feng Yan²,Xu Min²,Fu Wei¹,Zhang Wenbin²,Zhu Liangcheng²,Deng Zhongping²,Sheng Zelin²,Welihinda Ajith³,Sun Xun¹

Affiliation:

1. School of Pharmacy, Fudan University, 826 Zhangheng Road, Pudong New Area, Shanghai 201203, P. R. China

2. Egret Pharma (Shanghai) Co., Ltd, 4F, 1118 Halei Road, Zhangjiang Hi-Tech Park, Pudong New Area, Shanghai 201203, P. R. China

3. Theracos Inc., 550 Del Rey Avenue, Sunnyvale, California 94805-3528, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401780b

Reference49 articles.

1. Insulin Resistance as a Predictor of Age-Related Diseases