Synthesis and Antisense Properties of 2′-O-(2S-Methoxypropyl)-RNA-Modified Gapmer Antisense Oligonucleotides-Reference-Cited by-同舟云学术

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Synthesis and Antisense Properties of 2′-O-(2S-Methoxypropyl)-RNA-Modified Gapmer Antisense Oligonucleotides

Published:2014-05-28 Issue:9 Volume:9 Page:2040-2044
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Yu Jinghua,Pandey Sanjay K.,Khatri Hetal,Prakash Thazha P.,Swayze Eric E.,Seth Punit P.

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201402099/fullpdf

Reference17 articles.

1. Properties of Cloned and Expressed Human RNase H1

2. RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

3. Phosphorothioate Oligodeoxynucleotides: What Is Their Origin and What Is Unique About Them?

4. Ein neuer Zugang zu 2?-O-Alkylribonucleosiden und Eigenschaften deren Oligonucleotide

5. Antisense oligonucleotide pharmacokinetics and metabolism

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1. Current insights into transcriptional role(s) for the nutraceutical Withania somnifera in inflammation and aging;Frontiers in Nutrition;2024-05-03

2. Synthesis of 2′-O-[3-(N-methylsulfamoyl)propan-1-yl]ribothymidine as a potentially applicable 2′-modified nucleoside for antisense oligonucleotides;Bioorganic & Medicinal Chemistry;2022-11

3. Biological applications of xeno nucleic acids;Molecular BioSystems;2017

4. Effect of 2′- O -[2-[2-( N , N -dimethylamino)ethoxy]ethyl] modification on activity of gapmer antisense oligonucleotides containing 2′,4′-constrained 2′- O -ethyl nucleic acid;Bioorganic & Medicinal Chemistry Letters;2015-04

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