Optimized Inhibitors of MDM2 via an Attempted Protein‐Templated Reductive Amination-Reference-Cited by-同舟云学术

Optimized Inhibitors of MDM2 via an Attempted Protein‐Templated Reductive Amination

Published:2020-02-17 Issue:4 Volume:15 Page:370-375
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Vlag Ramon¹,Yagiz Unver M.¹^ORCID,Felicetti Tommaso¹²^ORCID,Twarda‐Clapa Aleksandra³^ORCID,Kassim Fatima¹,Ermis Cagdas¹,Neochoritis Constantinos G.⁴⁵^ORCID,Musielak Bogdan³^ORCID,Labuzek Beata³^ORCID,Dömling Alexander⁴^ORCID,Holak Tad A.³^ORCID,Hirsch Anna K. H.¹⁶⁷^ORCID

Affiliation:

1. Stratingh Institute for ChemistryUniversity of Groningen Nijenborgh 7 9747 AG Groningen The Netherlands

2. Department of Pharmaceutical SciencesUniversity of Perugia Via del Liceo 1 06123 Perugia Italy

3. Faculty of ChemistryJagiellonian University Gronostajowa 2 30-387 Krakow Poland

4. Department of Pharmacy, Drug Design groupUniversity of Groningen A. Deusinglaan 1 Groningen The Netherlands

5. Chemistry departmentUniversity of Crete 70013 Heraklion Greece

6. Department of Drug Design and OptimizationHelmholtz Institute for Pharmaceutical Research Saarland (HIPS) – Helmholtz Centre for Infection Research (HZI) Campus Building E8.1 66123 Saarbrücken Germany

7. Department of PharmacySaarland University Campus Building E8.1 66123 Saarbrücken Germany

Funder

Hartstichting

KWF Kankerbestrijding

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cmdc.201900574

Reference57 articles.

1. Protein-Templated Fragment Ligations-From Molecular Recognition to Drug Discovery