Dynamic combinatorial chemistry: a tool to facilitate the identification of inhibitors for protein targets-Reference-Cited by-同舟云学术

Dynamic combinatorial chemistry: a tool to facilitate the identification of inhibitors for protein targets

Published:2015 Issue:8 Volume:44 Page:2455-2488
ISSN:0306-0012
Container-title:Chemical Society Reviews
language:en
Short-container-title:Chem. Soc. Rev.

Author:

Mondal Milon¹²³⁴,Hirsch Anna K. H.¹²³⁴

Affiliation:

1. Stratingh Institute for Chemistry

2. University of Groningen

3. 9747 AG Groningen

4. The Netherlands

Abstract

Dynamic combinatorial chemistry enables efficient identification of protein binder(s) from a library of interconverting compounds. The library responds to the addition of the target by amplifying the strongest binder.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CS/C4CS00493K

Reference76 articles.

1. Dynamic Covalent Chemistry

2. Dynamic Combinatorial Chemistry

3. From supramolecular chemistry towards constitutional dynamic chemistry and adaptive chemistry

4. Dynamic Combinatorial Libraries: From Exploring Molecular Recognition to Systems Chemistry

5. Virtual combinatorial libraries: Dynamic generation of molecular and supramolecular diversity by self-assembly

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