Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs)-Reference-Cited by-同舟云学术

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Isoxazole-Based-Scaffold Inhibitors Targeting Cyclooxygenases (COXs)

Published:2016-05-02 Issue:11 Volume:11 Page:1172-1187
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Perrone Maria Grazia¹,Vitale Paola¹,Panella Andrea¹,Ferorelli Savina¹,Contino Marialessandra¹,Lavecchia Antonio²,Scilimati Antonio¹

Affiliation:

1. Dipartimento di Farmacia-Scienze del Farmaco; Università degli Studi di Bari “A. Moro”; Via E. Orabona 4 70125 Bari Italy

2. Dipartimento di Farmacia; “Drug Discovery” Laboratory; Università di Napoli “Federico II”; Via D. Montesano 49 80131 Napoli Italy

Funder

Ministero dell′Istruzione, dell′Università e della Ricerca Scientifica e Tecnologica

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference48 articles.

1. Selective COX-1 Inhibition: A Therapeutic Target to be Reconsidered

2. Cyclooxygenase Allosterism, Fatty Acid-mediated Cross-talk between Monomers of Cyclooxygenase Homodimers

3. Selective COX-1 inhibition as a target of theranostic novel diarylisoxazoles

4. General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model

5. PET radiotracer [18F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: Preliminary investigation

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2. A further pocket or conformational plasticity by mapping COX-1 catalytic site through modified-mofezolac structure-inhibitory activity relationships and their antiplatelet behavior;European Journal of Medicinal Chemistry;2024-02

3. A Convenient Synthesis of Novel Isoxazolidine and Isoxazole Isoquinolinones Fused Hybrids;Molecules;2023-12-22

4. Design and Development of COX-II Inhibitors: Current Scenario and Future Perspective;ACS Omega;2023-05-09

5. A Review on Green Synthesis and Biological Activities of Medicinally Important Nitrogen and Oxygen Containing Heterocycles;Current Organic Chemistry;2022-10

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