General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model-Reference-Cited by-同舟云学术

General role of the amino and methylsulfamoyl groups in selective cyclooxygenase(COX)-1 inhibition by 1,4-diaryl-1,2,3-triazoles and validation of a predictive pharmacometric PLS model

Published:2015-04 Issue: Volume:94 Page:252-264
ISSN:0223-5234
Container-title:European Journal of Medicinal Chemistry
language:en
Short-container-title:European Journal of Medicinal Chemistry

Author:

Perrone Maria Grazia,Vitale Paola,Panella Andrea,Fortuna Cosimo G.,Scilimati Antonio^ORCID

Publisher

Elsevier BV

Subject

Organic Chemistry,Drug Discovery,Pharmacology,General Medicine

Reference52 articles.

1. Selective COX-1 inhibition: a therapeutic target to be reconsidered;Perrone;Curr. Med. Chem.,2010

2. PET radiotracer [18F]-P6 selectively targeting COX-1 as a novel biomarker in ovarian cancer: preliminary investigation;Perrone;Eur. J. Med. Chem.,2014

3. Persistent accumulation of cyclooxygenase-1-expressing microglial cells and macrophages and transient upregulation by endothelium in human brain injury;Schwab;J. Neurosurg.,2002

4. Cyclooxygenase-1 and -2 differently contribute to prostaglandin E2 synthesis and lipid peroxidation after in vivo activation of N-methyl-d-aspartate receptors in rat hippocampus;Pepicelli;J. Neurochem.,2005

5. Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells;Calvello;Pharmacol. Res.,2012

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