The Effects of Conformational Constraints in the Polyamine Moiety of Philanthotoxins on AMPAR Inhibition-Reference-Cited by-同舟云学术

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The Effects of Conformational Constraints in the Polyamine Moiety of Philanthotoxins on AMPAR Inhibition

Published:2014-07-08 Issue: Volume: Page:n/a-n/a
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Franzyk Henrik,Grzeskowiak John W.,Tikhonov Denis B.,Jaroszewski Jerzy W.,Mellor Ian R.

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Reference35 articles.

1. Structure and synthesis of a potent glutamate receptor antagonist in wasp venom.

2. Partial purification of components from the paralysing venom of the digger wasp Philanthus triangulum F. (Hym. sphec.) and their action on neuromuscular transmission in the locust

3. Uncompetitive Antagonism of AMPA Receptors: Mechanistic Insights from Studies of Polyamine Toxin Derivatives

4. Modification of the philanthotoxin-343 polyamine moiety results in different structure-activity profiles at muscle nicotinic ACh, NMDA and AMPA receptors

5. Assessment of Structurally Diverse Philanthotoxin Analogues for Inhibitory Activity on Ionotropic Glutamate Receptor Subtypes: Discovery of Nanomolar, Nonselective, and Use-Dependent Antagonists

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Diversity of AMPA Receptor Ligands: Chemotypes, Binding Modes, Mechanisms of Action, and Therapeutic Effects;Biomolecules;2022-12-27

2. Synthesis and Biological Activities of Naturally Functionalized Polyamines: An Overview;Current Medicinal Chemistry;2021-06-08

3. Channel Blockers of Ionotropic Glutamate Receptors;Journal of Evolutionary Biochemistry and Physiology;2021-03

4. Philanthotoxin Analogues That Selectively Inhibit Ganglionic Nicotinic Acetylcholine Receptors with Exceptional Potency;Journal of Medicinal Chemistry;2019-06-05

5. Insect toxins – selective pharmacological tools and drug/chemical leads;Current Opinion in Insect Science;2018-12

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