1. Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, DK-2100 Copenhagen, Denmark, Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg 194223, Russia, Department for Molecular Biology, University of Aarhus, DK-8000 Aarhus, Denmark, Division of Molecular Toxicology, School of Biology, University of Nottingham, Nottingham NG7 2RD, United Kingdom, and Division of Molecular Biology, H. Lundbeck A/S, DK-2500 Valby, Denmark