The Role of Bridging Water and Hydrogen Bonding as Key Determinants of Noncovalent Protein-Carbohydrate Recognition

Author:

Ruvinsky Anatoly M.1ORCID,Aloni Ishita2,Cappel Daniel3ORCID,Higgs Chris4,Marshall Kyle5,Rotkiewicz Piotr1,Repasky Matt5,Feher Victoria A.4,Feyfant Eric1,Hessler Gerhard6,Matter Hans6

Affiliation:

1. Schrödinger, Inc.; 222 Third Street, Suite 2230 Cambridge MA 02142 USA

2. Schrödinger, Inc.; 120 West 45th Street New York NY 10036 USA

3. Schrödinger GmbH; Q7 23 68161 Mannheim Germany

4. Schrödinger, Inc.; 10201 Wateridge Circle, Suite 220 San Diego CA 92121 USA

5. Schrödinger, Inc.; 101 SW Main Street Portland OR 97204 USA

6. Sanofi-Aventis (Deutschland) GmbH; Integrated Drug Discovery (IDD), Synthetic Molecular Design, Building G838; Industriepark Höchst 65926 Frankfurt am Main Germany

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

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