Toward Second-Generation Cardiomyogenic and Anti-cardiofibrotic 1,4-Dihydropyridine-Class TGFβ Inhibitors-Reference-Cited by-同舟云学术

Toward Second-Generation Cardiomyogenic and Anti-cardiofibrotic 1,4-Dihydropyridine-Class TGFβ Inhibitors

Published:2019-02-28 Issue:8 Volume:14 Page:810-822
ISSN:1860-7179
Container-title:ChemMedChem
language:en
Short-container-title:ChemMedChem

Author:

Längle Daniel¹²,Werner Tessa R.³,Wesseler Fabian¹,Reckzeh Elena¹,Schaumann Niklas¹,Drowley Lauren⁴,Polla Magnus⁴,Plowright Alleyn T.⁴,Hirt Marc N.³,Eschenhagen Thomas³,Schade Dennis¹²^ORCID

Affiliation:

1. Department of Chemistry and Chemical Biology; Technische Universität Dortmund; Otto-Hahn-Str. 4 44227 Dortmund Germany

2. Department of Pharmaceutical and Medicinal Chemistry; Christian-Albrechts-Universität Kiel; Gutenbergstr. 76 24118 Kiel Germany

3. Department of Experimental Pharmacology and Toxicology; University Medical Center Hamburg-Eppendorf; Martinistr. 52 20246 Hamburg Germany

4. Cardiovascular, Renal and Metabolic Diseases IMED Biotech Unit; AstraZeneca Gothenburg; Pepparsleden 1 43 183 Mölndal Sweden

Funder

Bundesministerium für Bildung und Forschung

Verband der Chemischen Industrie

Publisher

Wiley

Subject

Organic Chemistry,General Pharmacology, Toxicology and Pharmaceutics,Molecular Medicine,Drug Discovery,Biochemistry,Pharmacology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/cmdc.201900036/fullpdf

Reference52 articles.

1. TGFβ family signaling: novel insights in development and disease

2. Development of TGF-β signalling inhibitors for cancer therapy

3. Getting to the Heart of the Matter

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