Development and validation of a UHPLC-MS/MS bioanalytical method to quantify in plasma the analgesic candidate PT-31 following a preliminary pharmacokinetic study in rats-Reference-Cited by-同舟云学术

Development and validation of a UHPLC-MS/MS bioanalytical method to quantify in plasma the analgesic candidate PT-31 following a preliminary pharmacokinetic study in rats

Published:2015-10-28 Issue:6 Volume:30 Page:852-856
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomed. Chromatogr.

Author:

Bessegato T. C.¹,Niehues M.²,Buqui G. A.²,Lopes N. P.²,Pitta I. R.³,Galdino S. L.³,Dalla Costa T.¹

Affiliation:

1. Programa de Pós-Graduação em Ciências Farmacêuticas; Universidade Federal do Rio Grande do Sul; Porto Alegre RS Brazil

2. Núcleo de Pesquisa de Produtos Naturais e Sintéticos; Universidade de São Paulo; Ribeirão Preto SP Brazil

3. Núcleo de Pesquisa em Inovação Terapêutica; Universidade Federal de Pernambuco; Recife PE Brazil

Funder

INCT-if/CNPq/Brazil

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

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3. Food and Drug Administration Guidance for Industry. Bioanalytical Method Validation 2001 http://www.fda.gov/downloads/Drugs/GuidanceComplianceRegulatoryInformation/Guidances/UCM070107.pdf

4. Perioperative use of selective α-2 agonists and antagonists in small animals;Lemke;Canadian Veterinary Journal,2004

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