Study of the in vitro metabolic profile of a new α2-adrenergic agonist in rat and human liver microsomes by using liquid chromatography-multiple-stage mass spectrometry and nuclear magnetic resonance-Reference-Cited by-同舟云学术

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Study of the in vitro metabolic profile of a new α2-adrenergic agonist in rat and human liver microsomes by using liquid chromatography-multiple-stage mass spectrometry and nuclear magnetic resonance

Published:2019-08 Issue: Volume:172 Page:67-77
ISSN:0731-7085
Container-title:Journal of Pharmaceutical and Biomedical Analysis
language:en
Short-container-title:Journal of Pharmaceutical and Biomedical Analysis

Author:

de O. Cardoso Josiane,da Silva Bianca F.,Venâncio Tiago,da Rocha Pitta Marina G.,da R. Pitta Ivan,Peccinini Rosângela G.,Oliveira Regina V.

Funder

Fundação de Amparo a Pesquisa do Estado de São Paulo

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Nível Superior

Publisher

Elsevier BV

Subject

Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry

Reference30 articles.

1. Clinical uses of alpha(2)-adrenergic agonists;Kamibayashi;Anesthesiology,2000

2. Dexmedetomidine;Bhana;Drugs,2000

3. Dexmedetomidine: a novel sedative-analgesic agent;Gertler;Proc. (Bayl. Univ. Med. Cent.),2001

4. A historical perspective: development of clonidine;Stähle;Best Pract. Res. Clin. Anaesthesiol.,2000

5. Epidural clonidine produces analgesia;Tamsen;Lancet,1984

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1. Genotoxic and Mutagenic Assessment of PT-31, a Molecule with Antipsychotic Potential;Drug Delivery Letters;2023-12

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