Leishmanicidal candidate LASSBio-1736, a cysteine protease inhibitor with favorable pharmacokinetics: low clearance and good distribution-Reference-Cited by-同舟云学术

Leishmanicidal candidate LASSBio-1736, a cysteine protease inhibitor with favorable pharmacokinetics: low clearance and good distribution

Published:2017-12-27 Issue:12 Volume:48 Page:1258-1267
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Moraes Barbra Sanches¹,Azeredo Francine Johansson²,Izoton Jessica Cristina¹,Amaral Marina³,Barreiro Eliezer de Jesus³,Freddo Rodrigo José⁴,Dalla Costa Teresa⁵,Lima Lídia Moreira³,Haas Sandra Elisa¹⁴

Affiliation:

1. Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Pampa , Uruguaiana , Brazil ,

2. Curso de Farmácia, Universidade Federal da Bahia , Salvador , Brazil ,

3. Laboratório de Avaliação e Síntese de Substâncias Bioativas, Universidade Federal do Rio de Janeiro , Rio de Janeiro , Brazil ,

4. Curso Farmácia, Universidade Federal do Pampa , Uruguaiana , Brazil , and

5. Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Rio Grande do Sul , Porto Alegre , Brazil

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/00498254.2017.1405465

Reference41 articles.

1. Design, synthesis and in vitro trypanocidal and leishmanicidal activities of novel semicarbazone derivatives

2. Treatment of canine leishmaniosis with aminosidine at an optimized dosage regimen: A pilot open clinical trial

3. Approaching Complete Inhibition of P-Glycoprotein at the Human Blood–Brain Barrier: An (R)-[11C]Verapamil PET Study

4. Prediction-Corrected Visual Predictive Checks for Diagnosing Nonlinear Mixed-Effects Models

5. Development and validation of a UHPLC-MS/MS bioanalytical method to quantify in plasma the analgesic candidate PT-31 following a preliminary pharmacokinetic study in rats

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