Coupling recombinase-mediated cassette exchange with somatic hypermutation for antibody affinity maturation in CHO cells-Reference-Cited by-同舟云学术

Coupling recombinase-mediated cassette exchange with somatic hypermutation for antibody affinity maturation in CHO cells

Published:2015-07-31 Issue:1 Volume:113 Page:39-51
ISSN:0006-3592
Container-title:Biotechnology and Bioengineering
language:en
Short-container-title:Biotechnol. Bioeng.

Author:

Chen Chuan¹²,Li Nan¹²,Zhao Yun¹,Hang Haiying¹

Affiliation:

1. Key Laboratory for Protein and Peptide Pharmaceuticals; National Laboratory of Biomacromolecules; Institute of Biophysics; Chinese Academy of Sciences; Beijing 100101 China

2. University of Chinese Academy of Sciences; Beijing China

Funder

National Basic Research Program of China

National Science and Technology Major Project

National Special Projects for Key Scientific Instruments and Equipment Development of Ministry of Science and Technology

Publisher

Wiley

Subject

Applied Microbiology and Biotechnology,Bioengineering,Biotechnology

Reference45 articles.

1. Whole IgG surface display on mammalian cells: Application to isolation of neutralizing chicken monoclonal anti-IL-12 antibodies;Akamatsu;J Immunol Methods,2007

2. Flp and Cre expressed from Flp-2A-Cre and Flp-IRES-Cre transcription units mediate the highest level of dual recombinase-mediated cassette exchange;Anderson;Nucleic Acids Res,2012

3. Protein evolution by hypermutation and selection in the B cell line DT40;Arakawa;Nucleic Acids Res,2008

4. Increased transcription levels induce higher mutation rates in a hypermutating cell line;Bachl;J Immunol,2001

5. Transcriptional properties of genomic transgene integration sites marked by electroporation or retroviral infection;Baer;Biochemistry,2000

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