Flp and Cre expressed from Flp–2A–Cre and Flp–IRES–Cre transcription units mediate the highest level of dual recombinase-mediated cassette exchange
Author:
Affiliation:
1. School of Biosciences, Louisiana Tech University, 1 Adams Blvd., Ruston, LA 71272, USA
Publisher
Oxford University Press (OUP)
Subject
Genetics
Link
http://academic.oup.com/nar/article-pdf/40/8/e62/25334286/gks027.pdf
Reference23 articles.
1. Use of mutated FLP recognition target (FRT) sites for the exchange of expression cassettes at defined chromosomal loci;Schlake;Biochemistry,1994
2. Stable and efficient cassette exchange under non-selectable conditions by combined use of two site-specific recombinases;Lauth;Nucleic Acids Res.,2002
3. Site-specific cassette exchange and germline transmission with mouse ES cells expressing phiC31 integrase;Belteki;Nat. Biotechnol.,2003
4. Current issues in mouse genome engineering;Glaser;Nat. Genet.,2005
5. Dual RMCE for efficient re-engineering of mouse mutant alleles;Osterwalder;Nat. Methods,2010
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