Dolastatin 15 from a Marine Cyanobacterium Suppresses HIF‐1α Mediated Cancer Cell Viability and Vascularization-Reference-Cited by-同舟云学术

Dolastatin 15 from a Marine Cyanobacterium Suppresses HIF‐1α Mediated Cancer Cell Viability and Vascularization

Published:2020-05-12 Issue:16 Volume:21 Page:2356-2366
ISSN:1439-4227
Container-title:ChemBioChem
language:en
Short-container-title:ChemBioChem

Author:

Ratnayake Ranjala¹,Gunasekera Sarath P.²,Ma Jia Jia³⁴,Dang Long H.¹⁵,Carney Thomas J.³⁴,Paul Valerie J.²^ORCID,Luesch Hendrik¹⁴^ORCID

Affiliation:

1. Department of Medicinal Chemistry and Center for Natural Products, Drug Discovery and Development (CNPD3)University of Florida 1345 Center Drive Gainesville FL 32610 USA

2. Smithsonian Marine Station 701 Seaway Drive Fort Pierce FL 34949 USA

3. Institute of Molecular and Cell Biology (IMCB)A*STAR, Proteos Singapore 138673 Singapore

4. Lee Kong Chian School of MedicineNanyang Technological University 59 Nanyang Drive Singapore 636921 Singapore

5. Department of MedicineUniversity of Florida Gainesville FL 32610 USA

Funder

National Institutes of Health

University of Florida

Florida Atlantic University

University of Guam

Publisher

Wiley

Subject

Organic Chemistry,Molecular Biology,Molecular Medicine,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/cbic.202000180

Reference58 articles.

1. Hypoxia signalling in cancer and approaches to enforce tumour regression

2. Targeting HIF-1 for cancer therapy

3. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation.

4. Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome

5. Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck

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