Evaluating futility of a binary clinical endpoint using early read‐outs
Author:
Affiliation:
1. Department of Applied Mathematics, Computer Science and StatisticsGhent University Ghent Belgium
2. Janssen R&DJanssen Pharmaceutica NV Beerse Belgium
3. Department of Medical StatisticsLondon School of Hygiene and Tropical Medicine London UK
Funder
VLAIO, Baekeland Mandate
Publisher
Wiley
Subject
Statistics and Probability,Epidemiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/sim.8366
Reference28 articles.
1. Assessment of futility in clinical trials
2. Futility approaches to interim monitoring by data monitoring committees
3. An aid to data monitoring in long-term clinical trials
4. A review of methods for futility stopping based on conditional power
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