1. Institute of Geriatrics, Affiliated Nantong Hospital of Shanghai University (The Sixth People's Hospital of Nantong) School of Medicine Shanghai University Nantong 226011 China
2. Cardiac Regeneration and Ageing Lab Institute of Cardiovascular Sciences Shanghai Engineering Research Center of Organ Repair School of Life Science Shanghai University Shanghai 200444 China
3. Division of Pain Management Huadong Hospital Affiliated to Fudan University Shanghai 200040 China
4. Cardiovascular Division of the Massachusetts General Hospital and Harvard Medical School Boston MA 02114 USA
5. Department of Cardiology Laboratory of Experimental Cardiology University Medical Center Utrecht 3508GA Utrecht The Netherlands