In Vitro–In Vivo Extrapolation of Clearance: Modeling Hepatic Metabolic Clearance of Highly Bound Drugs and Comparative Assessment with Existing Calculation Methods-Reference-Cited by-同舟云学术

In Vitro–In Vivo Extrapolation of Clearance: Modeling Hepatic Metabolic Clearance of Highly Bound Drugs and Comparative Assessment with Existing Calculation Methods

Published:2012-02 Issue:2 Volume:101 Page:838-851
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Poulin Patrick,Kenny Jane R.,Hop Cornelis E.C.A.,Haddad Sami

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference58 articles.

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4. Comparison of clearance predictions using primary cultures and suspensions of human hepatocytes;Blanchard;Xenobiotica,2005

5. Prediction of hepatic clearance using cryopreserved human hepatocytes: A comparison of serum and serum free incubations;Blanchard;J Pharm Pharmacol,2006

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